OMB Individually Reported

DeepEMhancer

Low riskExact public inventory row

Description

Automated screening of CryoEM specimens

Detailed example

Input is cryoEM imaging data, outputs are enhanced images.

AI / analytics pattern

Other

Automation level / stage

c) Deployed – The use case is being actively authorized or utilized to support the functions or mission of an agency.

Expected benefit

Open-source software that is used to obtain final "sharpened" cryoEM maps (https://github.com/rsanchezgarc/deepEMhancer). This algorithm uses a ML model to estimate the noise in the model and refine the local areas of the map and is utilized by the Cryo-EM core in support of research projects within NIEHS DIR and DTT laboratories.

Controls / human review

ATO: No; PIA: Not published

Data needed

Models were trained using publicly available data.