OMB Individually Reported

CI5: Development and refinement of toolkits for routine use in the EHR and claims Data Partner network

Low riskExact public inventory row

Description

This project is designed to solve the problem of inconsistent or inefficient data analysis capabilities across the EHR and claims Data Partner network. It aims to create standardized, reliable analytical tools that can be routinely deployed across different data partners to improve the consistency, quality, and efficiency of pharmacoepidemiologic analyses within the Sentinel System.

Detailed example

Regularized machine learning tools (e.g., Least Absolute Shrinkage and Selection Operator (LASSO)-based models) combined with targeted learning methods for improved large-scale covariate adjustment

AI / analytics pattern

Natural Language Processing: AI that processes, interprets, and shares information in human language.

Automation level / stage

c) Deployed – The use case is being actively authorized or utilized to support the functions or mission of an agency.

Expected benefit

improved confounding control when using Electronic Health Record (EHR) data for drug safety studies, leading to more reliable conclusions about medication risks and benefits in real-world populations.

Controls / human review

ATO: Yes; PIA: Not published

Data needed

Electronic Health Record (EHR) Data Elements